Joba makes his second start of the year. He's pitched five times against Cleveland, but all in relief. In six innings, he's allowed three runs (4.50 ERA).
Anthony Reyes makes his third start, but has never faced the Yankees. He has a career 89 ERA+ over 261 ML innings, including 45 starts and 15 relief appearances.
So both teams have very little knowledge of the starting pitchers. We might see hitters feeling them out and taking a lot of pitches early on.